γ-tubulin，which is usually in the form of γ-tubulin small complex (γTuSC) and γ-tubulin ring complex（γTuRC）, targeting to microtubule organizing centers (MTOCs) via a set of γ-tubulin complex binding proteins (GTBPs), is an ubiquitous protein in eukaryotes and plays an important role in the microtubule nucleation and assembly of mitosis spindle. Recent progress in the structure, molecule models and functions of γ-tubulin complexes is reviewed.