A Stochastically Unequal Interval Four-state Hopping Model of Molecular Motor
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This work was supported by grants from The National Natural Sciences Foundation of China (10075007), Hebei Provincial Nature Science Foundation (102001) and Doctoral Fund of Hebei Province (00547001D).

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    Abstract:

    The stochastic master equation approach to molecular motor's directed motion is used and a periodic one-dimensional four-state stochastically unequal interval hopping model is studied. The drift velocity V, the diffusion constant D and the randomness parameter r of the steady state are all be obtained. By comparing the simulated curve with experiment about drift velocity V, diffusion constant D and randomness parameter r versus [ATP] and external load F, the kinetic behaviors of a molecular motor under external load F are qualitatively analyzed.

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ZHAN Yong, WU Wei-Xia, ZHAO Tong-Jun, GUAN Rong-Hua, MEI Jun-Ping. A Stochastically Unequal Interval Four-state Hopping Model of Molecular Motor[J]. Progress in Biochemistry and Biophysics,2003,30(3):416-421

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  • Received:October 29,2002
  • Revised:January 10,2003
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