This work was supported by grants from National Basic Research Program of China (2001CB510208), The National Natural Science Foundation of China (30370642, 30240056), Ministry of Education of China for Outstanding Scholars of New Era (2002-48), Key Research Program from Science and Technology Committee of Hunan (02SSY2001-1) and Key Research Program from Public Health Bureau of Hunan Province (Z02-04).
Clinical proteomics is the application of proteomics in clinical medicine, which focuses on the prevention, diagnosis and therapy of disease. Cancer has been the primary research object in clinical proteomics. Because biomarker is invaluable in early diagnosis of cancer, one of the central goals in clinical proteomics is to discover appropriate biomarker and the interest shifts to looking for multi-biomarkers combined. Study design, sample collection and pre-process in clinical proteomics and the application and progress of clinical proteomics technology have been introduced.
LI Feng, Yang Fang, XIAO Zhi-Qiang, CHEN Zhu-Chu. Clinical Proteomics: The Application of Proteomics in The Research of Clinical Medicine[J]. Progress in Biochemistry and Biophysics,2006,33(1):5-9
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