Progress in Genetics of Essential Tremor

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Progress in Genetics of Essential Tremor
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Fund Project:This work was supported by grants from The National Natural Science Foundation of China(30871351, 30971534), Trans-Century Training Program Foundation for the Talents by The State Education Commission (NCET-080563), The Fund for Distinguished Young Scholar of Hunan Province (09JJ1005), The Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry (H.D.), Sheng Hua Scholars Program and Outstanding Youth Foundation of Central South University, China (H.D.) and Aid program for Science and Technology Innovative Research Team in Higher Educational Institutions of Hunan Province

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Abstract:

Essential tremor is one of the most common neurological disorders which the causes remain unknown. The clinical feature is heterogeneous and many ET patients have positive family history. Thus far, three gene loci have been identified and two susceptibility genes including DRD3 (the dopamine receptor D3 gene) and LINGO1 (the Leucine-rich repeat-and lg domain-containing NOGO receptor-interacting protein 1 gene) have been reported recently. The genetics of essential tremor will be summarized.

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LIANG Hui, GUO Yi, DENG Hao. Progress in Genetics of Essential Tremor[J]. Progress in Biochemistry and Biophysics,2011,38(1):5-10

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Received:February 08,2010
Revised:August 04,2010
Accepted:
Online: August 17,2010
Published: January 20,2011

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