The year 2010 marks the sixtieth anniversary for the publication of Science in China series journals, and meanwhile the Science in China Series C: Life Sciences took a new name as Science China Life Sciences (SCLS in short). Simultaneously, it has been reformed to make a new start for this journal in its long history. The journal has appeared with a new face to the readers and authors in both the novel publishing style and the highly qualified articles. An extensive review was given to the journal's specific progress in the year 2010 by highlighting some of the representative publications.