Department of Orthopedics and Department of osteocarcinoma institute,The Second Xiangya Hospital of Central South University,Department of Orthopedics and Department of osteocarcinoma institute,The Second Xiangya Hospital of Central South University,Department of Nephrology,Zhuzhou NO hospital,Department of Orthopedics and Department of osteocarcinoma institute,The Second Xiangya Hospital of Central South University,Department of Orthopedics and Department of osteocarcinoma institute,The Second Xiangya Hospital of Central South University,Department of Orthopedics and Department of osteocarcinoma institute,The Second Xiangya Hospital of Central South University,Department of Orthopedics and Department of osteocarcinoma institute,The Second Xiangya Hospital of Central South University,Department of Orthopedics and Department of osteocarcinoma institute,The Second Xiangya Hospital of Central South University

This work was supported by grants from The National Natural Science Foundation of China (30571883) and Hunan Provincial Natural Science Foundation of China (09JJ3081)