Department of Geriatric Endocrinology,General Hospital of PLA,Department of Geriatric Endocrinology,General Hospital of PLA,Department of Geriatric Endocrinology,General Hospital of PLA
This work was supported by grants from The National Natural Science Foundation of China (81173625, 81270424)
Glucagon-like peptide-1(GLP-1) is an important incretin hormone that secreted from intestinal L cells. Numerous studies have proven that GLP-1 increases β-cell mass through promoting β-cell proliferation and inhibiting β-cell apoptosis, besides stimulating insulin secretion. This review focuses on the molecular mechanism of GLP-1 induced β-cell protection.
MIAO Xin-Yu, LIU Yu, LI Chun-Lin. Advances on Molecular Mechanism of Glucagon-like Peptide-1 Induced Pancreatic β-cell Protection[J]. Progress in Biochemistry and Biophysics,2013,40(6):
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