Institute of Cardiovascular Research of University of South China,Institute of Cardiovascular Research，University of South China, School of Nursing,University of South China,Institute of Cardiovascular Research，University of South China;Department of Physiology，Institute of Cognition and NervousSystem Disease, Medical College，University of South China,Department of Diagnostics, Medical college, University of South China,Institute of Cardiovascular Research, Laboratory for Atherosclerology of Hunan Province, Life Science Research Center, University of South China

The National Natural Science Foundation of China(81170278, 81070220, 81300158)