Recent Research Progress of Ca<sup>2+</sup> Permeable Channels

Home > Archive>Volume 43, Issue 12, 2016 >1129-1138

Recent Research Progress of Ca2+ Permeable Channels
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Affiliation:State Key Laboratory of Membrane Biology,Peking University,State Key Laboratory of Membrane Biology,Peking University,State Key Laboratory of Membrane Biology,Peking University,State Key Laboratory of Membrane Biology,Peking University
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Fund Project:This study was supported by the State Major Research and Development Program (2016YFA0500401), National Natural Science Foundation of China (31630035, 81370203, 81461148026, and 31327901) and the Project of Beijing Municipal Science and Technology Commission (Z141100000214006)

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Abstract:

Ca²⁺ is a universal intracellular messenger playing important roles in nearly all biological processes. Recent studies of structural biology have resolved near-atom-resolution structure of many Ca²⁺ permeable ion channels in their different open/close states. These advances have revealed the molecular mechanisms for the channel construction, operation, function and regulation, and provide a fundamental basis for understanding the process of Ca²⁺ signaling and related diseases.

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FAN Xue-Xin, YANG Lei, XIANG Bin, WANG Shi-Qiang. Recent Research Progress of Ca²⁺ Permeable Channels[J]. Progress in Biochemistry and Biophysics,2016,43(12):1129-1138

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Received:November 21,2016
Revised:December 17,2016
Accepted:December 19,2016
Online: December 22,2016
Published: December 20,2016

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