A method of focusing strongly scattered light through turbid media based on spatial light wavefront modulation was proposed in the field of biophysical imaging. The content and procedure of this new method was detailed described. The strict optical theory indicates that the focusing result is better if the effect of interference is considered more intensely. The experiment also indicates this phenomenon. In addition, the experiment reveals that under the same conditions, the more the number of pixels controlled on spatial light modulator, the better the focusing result is. This new method has higher signal-to-noise ratio than other methods. The result of focusing and the phase board uploaded on spatial light modulator are displayed in the paper. At the same time, the convergence rate of focusing is much faster than other methods. That is mainly because our method has considered interference and the focusing result is the superposition of all pixels modulated on spatial light modulator. Therefore, we think that it will provide a new idea for the research of biophysics imaging.