College of Physics Science and Technology, Shenyang Normal University,College of Physics Science and Technology, Shenyang Normal University,College of Physics Science and Technology, Shenyang Normal University,College of Science, Huazhong Agricultural University,College of Physics Science and Technology, Shenyang Normal University
This work was supported by grants from The National Natural Science Foundation of China (11604112), Liaoning Natural Science Foundation (2015020715), Shenyang Normal University Scientific Research Program (L201514), Doctor Start-up Fund of Shenyang Normal University (51600209), and Talent Support Program of Shenyang Normal University (BS201433)
The full-field optical coherence tomography (FF-OCT) is one of the best technologies to study the morphological development of the early embryo, while its images suffer from some noises. Due to the noises, the boundaries between the different organizations in the early embryo are ambiguous, which would cause interference of organization segmentation. To solve this problem, this paper processed full-field OCT images of early embryos with the median filter, wiener filter and anisotropic diffusion algorithm, and evaluated the noise reduction effect using the signal-to-noise ratio, the mean square error, peak signal to noise ratio and edge retention index. It was shown that early embryo images after noise reduction with anisotropic diffusion algorithm kept most of the original information with relatively clear boundaries. Therefore, anisotropic diffusion algorithm is suggested to be the best denoising method for FF-OCT imaging in terms of the visual effect.
WANG Yi-Ming, WANG Ting, YU Ji, ZHANG Shu, TIAN Ning. Boundary Deblurring of Full-field OCT Image of Early Embryo[J]. Progress in Biochemistry and Biophysics,2018,45(10):1078-1082
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