Research Progress on Bacterial DNA Methylation

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Research Progress on Bacterial DNA Methylation
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Affiliation:Department of Microbiology and Immunology, Institutes of Medical Sciences, Shanghai Jiao Tong University, Shanghai,Department of Microbiology and Immunology, Institutes of Medical Sciences, Shanghai Jiao Tong University, Shanghai
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Fund Project:This work was supported by grants from The National Natural Science Foundation of China (81772140) and National Basic Research Program of China (2015CB554203)

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Abstract:

DNA methylation is a robust type of gene regulation and plays an important role in physiological processes. This review summarizes the origin of DNA methylation in bacteria, DNA methyltransferases, transcriptional and post-transcriptional regulatory mechanisms by DNA methylation, comments on research progress on DNA methylation functions as well as detection methods. The achievements will be significant for understanding bacterial epigenetic regulation and controlling bacterial infections in the future.

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ZHANG Wen-Ting, YAO Yu-Feng. Research Progress on Bacterial DNA Methylation[J]. Progress in Biochemistry and Biophysics,2018,45(10):1026-1038

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Received:May 04,2018
Revised:July 07,2018
Accepted:July 09,2018
Online: October 22,2018
Published: October 20,2018

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