1.1)CAS Key Laboratory of Mental Health,Institute of Psychology,Chinese Academy of Sciences,Beijing 100101,China;2.2)Department of Psychology,University of Chinese Academy of Sciences,Beijing 100049,China
This work was supported by grants from the Beijing Municipal Science and Technology Commission(Z171100000117014),the National Key Research and Development Program of China(2016YFC1307200)and the Strategic Priority Research Program of Chinese Academy of Sciences (XDB32010300).
Posttraumatic stress disorder (PTSD) can impair cognitive functions such as memory, attention, and executive control, and induce the abnormality of brain activity and functional connectivity between brain regions. Although pharmacotherapy and psychotherapy can achieve a certain degree of therapeutic effects, there are problems such as side effects and delayed onset of action. Transcranial magnetic stimulation (TMS) has attracted more and more attention as a new intervention method for posttraumatic stress disorder. Here we systematically review the studies of the effects of TMS in the intervention of PTSD and the regulation of cognitive function and brain activity. The issues of TMS in the intervention of PTSD were discussed, including the stimulation pattern, the stimulation target and the efficacy evaluation. In the future, the intervention programs with long-term clinical improvement can be explored by applying more effective techniques for precise targeting, establishing integrative and effective evaluation systems, and combining new memory theories.
LU Ping-Ping, WANG Liang. Research Progress of Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder[J]. Progress in Biochemistry and Biophysics,2020,47(4):319-334
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