Research Progress of New Coronavirus SARS-CoV-2 Detection Technology
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1.1)Shandong Academy of Pharmaceutical Sciences, Key Laboratory of Biopharmaceuticals, Engineering Laboratory of Polysaccharide Drugs, National-Local Joint Engineering Laboratory of Polysaccharide drugs, Postdoctoral Scientific Research Workstation, Jinan 250101, China;2.2)Shandong Freda Pharmaceutical Group Company, Jinan 250101, China

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This work was supported by grants from Shandong Provincial Key Research and Development Program(2019GSF107040)and Jinan Innovation Team Project of Colleges and Universities(2019GXRC038).

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    Abstract:

    The new coronavirus SARS-CoV-2 has a strong transmission ability and has been confirmed to be transmissible from person to person. Asymptomatic carriers can also be a source of transmission. Rapid and accurate diagnosis of the new coronavirus is particularly important to control the outbreak. Based on the relevant research progress at home and abroad, this paper analyzes and combs the four major detection technologies of new coronaviruses such as fluorescent PCR, isothermal amplification, Cas enzyme technology and immunoassay, in order to provide references and ideas for the diagnosis, prevention and control of new coronaviruses and other epidemic viruses.

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ZHANG Xiao-Yuan, ZHANG Yan-Yan, ZHANG Xiao-Gang, LIU Xia, CHEN Mian, LIU Fei, ZHANG Dai-Zhou, LING Pei-Xue. Research Progress of New Coronavirus SARS-CoV-2 Detection Technology[J]. Progress in Biochemistry and Biophysics,2020,47(4):275-285

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History
  • Received:March 11,2020
  • Revised:March 31,2020
  • Accepted:April 02,2020
  • Online: April 03,2020
  • Published: April 20,2020