Research progress of light induced corneal cross-linking and its detection technology
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Center for Biomedical Photonics & College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China

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    Abstract:

    More and more people suffer from myopia due to keratoconus disease. Common correction methods include wearing myopia glasses, contact lenses, etc. With the progress of science and technology, the use of light for refractive correction of myopia and other ophthalmic diseases has become a common clinical method. The light can induce the cross-linking of corneal collagen, so as to treat keratoconus disease and improve the visual acuity of patients. At the same time, this method has become a novel research focus due to its merits of non-invasive and low dependence on operator ability. In this paper, the basic principle and development of light-induced corneal crosslinking are introduced, meanwhile the principles of various existing cross-linking methods and corneal detection techniques are analyzed, and the advantages and disadvantages of the existing cross-linking methods and detection methods are discussed. Finally, the latest development of light-induced corneal crosslinking and detection technology is systematically discussed, and prospected the future development trend of light-induced corneal crosslinking and detection technology.

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Huang Yang Rui, Guo Yong, Yang Zhi Gang, Yan Wei, Qu Jun Le. Research progress of light induced corneal cross-linking and its detection technology[J]. Progress in Biochemistry and Biophysics,2021,48(3):246-262

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History
  • Received:June 15,2020
  • Revised:August 04,2020
  • Accepted:August 13,2020
  • Online: April 26,2021
  • Published: March 20,2021