From Type 2 Diabetes toRelated Cognitive DysfunctionImpairment and Therapy Opportunities withof Traditional Chinese Medicines

doi:10.16476/j.pibb.2020.0265

Home > Archive>Volume 47, Issue 8, 2020 >743-761. DOI:10.16476/j.pibb.2020.0265

From Type 2 Diabetes toRelated Cognitive DysfunctionImpairment and Therapy Opportunities withof Traditional Chinese Medicines
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                        10.16476/j.pibb.2020.0265
                    
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Affiliation:1.1)Affiliated TCM Hospital/School of Pharmacy/Sino-Portugal TCM International Cooperation Center, Southwest Medical University, Luzhou 646000, China;2.2)Research Center of Pharmacology and Toxicology, Peking Union Medical College, Institute of Medicinal Plant Development, Beijing 100193, China;3.3)Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan;4.4)National Key Laboratory of Human Factors Engineering, China Astronaut Research and Training Center, Beijing 100094, China;5.5)Hunan Provincial Research Center for Safety Evaluation of Drugs, Changsha 410331, China
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Abstract:

Diabetes mellitus is one of the most devastating metabolic disorders affecting physiology of several organs. Type 2 diabetes (T2D) is the most prevalent type of diabetes worldwide, and . T2D usually affects elder population. and cClinical and basic studies have highlighted its involvement in cognition decline especially learning and memory. T2D individuals are at high risk to develop dementia as compare to normal population. This paper reviews highlighted the recent studies which demonstrated cognitive decline among T2D individuals and in animal models, including the related mechanisms and, the therapies, to make a better knowledge on T2D cognitive complication.

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Ayaz Ahmed, LI Yu-Jiao, LI Shan-Shan, WEI Shan-Shan, WANG Meng-Di, YANG Si-Jin, CHEN Shan-Guang, ZENG Gui-Rong, Mudassar Azhar, LIU Xin-Min, WANG Qiong. From Type 2 Diabetes toRelated Cognitive DysfunctionImpairment and Therapy Opportunities withof Traditional Chinese Medicines[J]. Progress in Biochemistry and Biophysics,2020,47(8):743-761

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Received:July 27,2020
Revised:July 27,2020
Accepted:July 27,2020
Online: November 26,2020
Published: August 20,2020

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