Research on Measurement of Optical Biological Parameters of Eyes Based on Low-coherence Light Interference
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1)School of Physics and Optoelectronic Engineering, Foshan University, Foshan 528000, China;2)School of Mechatronic Engineering and Automation, Foshan University, Foshan 528000, China

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This work was supported by grants from Guangdong Science and Technology Plan (X200051UZ200) and Guangdong Science and Technology Innovation Strategy Special Fund (pdjh2021a0520).

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    Abstract:

    Objective The axial length (AL) and the corneal curvature radius (CR) in the optical biological parameters of the eye can be used as two important parameters for the prevention and monitoring of ocular myopia. In order to improve the speed and accuracy of measuring the length of eye axis and to achieve high precision of corneal curvature simultaneously dynamic measurement, This paper proposes a system for measuring optical biological parameters of the eye based on low-coherence light interference technology.Methods The system uses a rotating optical delay line to quickly change the optical path of the reference light, and uses a standard part with a curvature radius of 8 mm to calibrate the vertex of the human cornea to the distance between the target ring and the interference signal of the cornea trigger the camera and the data acquisition card to achieve synchronous acquisition, thereby realizing rapid measurement of the axial length and precise positioning of the distance between the target ring and the corneal vertex, while ensuring the magnification of the imaging system constant and real-time data collection.Results Experimental results show that this low-coherence optical interferometry system can measure the axial length and corneal curvature radius in real time. The axial length error is less than 40 μm, and the human corneal curvature radius variance is 2.082 36×10-2 μm.Conclusion The system measures AL and CR quickly and accurately, which may play an important role in the prevention and monitoring of myopia.

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HU Ji-Ye, CHEN Long, HUANG Li-Yuan, DING Wen-Zheng, HUANG Ming-Bin, ZHANG Hao, ZENG Ya-Guang, TAN Hai-Shu. Research on Measurement of Optical Biological Parameters of Eyes Based on Low-coherence Light Interference[J]. Progress in Biochemistry and Biophysics,2022,49(9):1810-1820

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History
  • Received:July 22,2021
  • Revised:November 12,2021
  • Accepted:November 24,2021
  • Online: September 21,2022
  • Published: September 20,2022