1) College of Basic Medicine, Southwest Medical University, Luzhou 646000, China;2) Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China;3.4) University of Chinese Academy of Sciences, Beijing 100049, China;4.3) Translational Medical Center, Weifang Second People’s Hospital, Weifang 261041, China

This work was supported by a grant from Beijing Brain Project (Z161100000217141).