Abstract:In this paper, we have studied the changes of F-actin assembly in ascitic liver cancer cells of mouse under the action of extrinsic laminin and cis-platin. The results shows that after the extrinsic laminin combined with its receptors they can promote the assembly of F-actin, resulting in the increase of the amount of the F-actin, that cis-platin, one of the multiple-targeted antitumor drugs, inhibits the assembly of F-actin after linking with F-actin and that under the action of laminin and Cis-platin, the assembly tends to stability and the amount of the F-actin remains unchanged. This study gives a direct evidence for the opposite action of extrinsic laminin and cis-platin on the assembly of F-actin in ascitic liver cancer cells of mouse.

Abstract:The treatment of human erythrocyte membranes with superoxide anion (O₂^-_·) produced by pyrogallic acid, pH8.4, caused peroxidative damages to cell membranes, such as increase of fluorescent substance on membranes, formation of high molecular polymers (HMP) due to membrane protein cross-linking. However, these were almost not induced after adding a certain amount of Na₂SeO₃. It is suggested the anti-peroxidation effect of Na₂SeO₃ on erythrocyte membranes.