Abstract:A sensitive and specific immunoblot assay was used to analyze 33 cases of immune reactions between sera of Schistosomiasis Japonica patients and schistosome Japonicum egg (SEA) and adult (SWAP) antigens. The assays consists of SDS-PAGE and Western blot. The sensitivity of SEA reaction is 100%, while that of SWAP is 97%, with negative reactivity in the control sera. In most cases (28/33), SEA reactive to patient sera show three wide bands at 180,54 and 32kD while in the case of SWAP it shows two wide bands at 190 and 64kD in 26 cases(26/32). In most patients (21/24) with acute schistosomiasis Japonica, an additional wide band is seen at 34kD. These results suggest clinical value of Western Blot in the diagnosis of schistosomiasis Japonica.

Abstract:In order to study effect of plasma lipids on ATPases activities in erythrocyte membrane, contents of plasma TC, LDL-C and HDL-C and activities of Na⁺-K⁺- and Ca²⁺-Mg²⁺-ATPase were determined in 28 hypercholesterolemia patients and 16 control.The Na⁺-K⁺- and Ca²⁺-Mg²⁺-ATPase activities were reduced in these patients. Negative correlations were shown between two ATPase activities and plasma TC and LDL-C levels, but positive correlation was shown between Na⁺-K⁺-ATPase activity and plasma HDL-C level in all groups. These studies may be important for probing into mechanism of atherosclerosis formation and prevention and cure of this disease. This problem is discussed in the paper.

Abstract:The cell electrophoresis and dielectrophoresis of the erythrocytes in rabbits with hypercholesterolemia were measured. The results ihdicated that the aggregation of these erythrocytes was inereased, while thier deformation and membrane fluidity were decreased compared with the control. It suggests that the hypercholesterolemia may be one of the reasons which causes the thrombosis. The results also showed that 8501 (the effective principle of the chinese herb) could regulate above changes of the erythrocytes, which implied that 8501 may have benefit in preventing and treating thrombosis and atherosclerosis.