Vol.45,No.12,2018

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Cover Story：A cadmium-responsive metal ion transporter OsPDR, which was highly upregulated in the shoot of rice (Oryza sativa ssp. japonica cv. Nipponbare) at 24 h after treatment with 50 μmol/L Cd, was identified in cadmium-responsive transcriptome profiles analyzed by RNA-Seq. In this study, we isolated OsPDR from rice (Oryza sativa cv. Nipponbare) and the metal ions transport activity of OsPDR was analyzed. The results of metal tolerance experiments showed that overexpression of OsPDR can enhance yeast’s tolerance to Co, but not to Zn, Ni or Cd, and higher accumulation of Co was observed compared to the empty vector-transformed yeast as determined by inductively coupled plasma mass spectrometry (ICP-MS). The EGFP-OsPDR fusion protein was localized to the vacuolar membrane using confocal microscopy. These data suggested that OsPDR might play an important role in Co homeostasis. Additional studies are needed to understand the function of OsPDR in plants.

Reviews and Monographs

Advances in Understanding The Mechanisms of Deep Brain StimulationFENG Zhou-Yan, GUO Zhe-Shan and WANG Zhao-Xiang  [Abstract][PDF][HTML]

Sequestration of Cellular Essential Proteins or RNA by Polyglutamine-Expanded Protein AggregatesYUE Hong-Wei and HU Hong-Yu  [Abstract][PDF][HTML]

Application of Deep Learning in Biological Mass Spectrometry and ProteomicsZHAO Xin-Yuan, QIN Wei-Jie and QIAN Xiao-Hong  [Abstract][PDF][HTML]

Epigenetic Modification of Redox Regulation in Breast CancerGOU Xiao-Meng, SUN Hong-Liang, ZHANG Zhong-Guo, XUE Xin-Yu, HAO Jing-Zhi and ZHANG Hong-Sheng  [Abstract][PDF][HTML]

Equilibrium of Methionine Adenosine Transferase 1A / 2A and Hepatocellular CarcinomaLI Zi-Han, XIONG Ting, XIONG Xiao-Li, LU Zi-Xian, ZHOU Zhi-Gang and TU Jian  [Abstract][PDF][HTML]

The Physiological Functions of Phytosterols and Their Underlying Mechanism of Regulating MitochondriaLOU Jing, CUI Ya-Juan, LIU Jian-Kang and ZHAO Lin  [Abstract][PDF][HTML]

Phosphoproteomics Based on Mass Spectrometry(MS): Enrichment, Detection, Assignment and QuantificationSHI Wen-Hao, TONG Meng-Sha, LI Kai, WANG Yu-Shen and DING Chen  [Abstract][PDF][HTML]

Research Papers

Heterologous Expression of OsPDR Enhances The Tolerance to Cobalt in YeastTIAN Si-Qi, QIAO Kun, WANG Fan-Hong, LIANG Shuang, WANG Hong and CHAI Tuan-Yao  [Abstract][PDF][HTML]

Identification of Reference and Biomarker Proteins in Nitrogen Depletion-mediated Triacylglycerol Biosynthesis in Chlamydomonas reinhardtiiSHI Jia-Nan, DU Tie-Min, CHEN Yue, ZHOU Yan, YANG Ya-Ru, LI Li-Yun, DOU Shi-Juan, LIU Li-Juan and LIU Guo-Zhen  [Abstract][PDF][HTML]

Techniques and Methods

A Method for Identifying Ｔhe Topology of Etoposide-induced Protein 2.4 Using Split mNeonGreen2LIU Qi, XU Ping-Yong and YUAN Lin  [Abstract][PDF][HTML]
©：Progress in Biochemistry and Biophysics
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